Medical Questions » Heart Questions » Question No. 1318
Question:The hospital has advised my wife, who is 73, to come of f garlic, CoQ10, glucosamine, high vitamin C, calcium and omega-3, as they conflict with the warfarin she is taking. What is your view?
Answer:A Warfarin is a blood-thinning drug that interferes with the action of vitamin K, which the body synthesises in the gut, and controls normal blood clotting. It is also used to kill rats by overthinning their blood. I know of no reason why vitamin C, calcium or Co-enzyme Q10 would conflict with warfarin.

That leaves the omega-3s and garlic, and these are a somewhat different story. Omega-3 fats naturally reduce platelet adhesion, so they are an alterna- tive blood-thinning agent. Garlic, too, has blood-thinning properties. But that doesn' t mean these need be barred completely. Ideally, one would want to lower warfarin and increase omega-3s, which have numerous other positive effects on reducing risk of a heart attack or stroke. However, that is something your wife would need to discuss with her doctor or cardiologist. Since her doctor has not mentioned avoiding fish or seeds, both of which contain omega-3 fats, the question is also one of quantity and hence level of effect.

Eating garlic in, say, pasta sauces and stir-fries, shouldn' t cause a problem. And I doubt that taking an omega-3 supplement every day providing 200mg of EPA and 150mg of DHA (adding up to 350mg of omega-3 fats), or eating fish three times a week and a spoonful of ground flax seeds a day on cereal, would have any harmful effect. I don' t advise larger amounts, however. It would be wise for your wife to monitor her platelet adhesion index and if this goes too low, to lower the warfarin dose accordingly.

       
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