If you are prone to allergic or inflammatory health problems such as eczema, asthma or hay fever, MSM may provide substantial relief. People with chronic pain, perhaps frequent headaches, back or muscle pain, are reporting major improvement after supplementing 1 to 3g a day. Start with 1g for a week, then double the dose. However, don' t expect results overnight. It often takes a week or two to work, and a few people have reported a flare-up of symptoms for a couple of days as sulphur helps the body detoxify and repair old injuries.