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Sickle Cell Anemia

Medical Questions » Sickle Cell Anemia
Name: Sickle Cell Anemia
Also known as: Hemoglobin S Disease
A form of abnormal red cell development in Negroes.
Causes of Sickle Cell Anemia
Inherited condition that causes red blood cells to become sickle shaped (like a crescent moon) rather than round because of an abnormal form of hemoglobin called hemoglobin S. The abnormal gene is found only in Negroes.
Symptoms of Sickle Cell Anemia
Victims are tired and weak, have large spleens, may become jaundiced (yellow), heal poorly, develop gallstones easily and cope poorly with infections.
Tests for Sickle Cell Anemia
Adults carrying the abnormal gene can be identified by blood tests, and if two carriers marry, one in four of their children will suffer from sickle cell anemia. Can be diagnosed before birth by amniocentesis or other tests on the unborn child. After birth, examining blood under a microscope reveals the abnormal cells.
Treatment for Sickle Cell Anemia
Treatment with folic acid supplements and occasional transfusions control most cases. Maintaining adequate water intake and treating infections early are important.
Complications of Sickle Cell Anemia of its treatment
Clumping of the abnormal red cells may block small arteries, cause severe pain in wide areas of the body and permanently damage the heart, liver and other organs.
Likely Outcome of Sickle Cell Anemia
There is no cure but its effects can usually be controlled. Interestingly, the disease gives protection against malaria.
       
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